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Comparative Study
. 1983 Sep 15;214(3):1007-9.
doi: 10.1042/bj2141007.

UDP-glucuronyltransferase activity exhibits two developmental groups in liver from foetal rhesus monkeys

J E Leakey, Z R Althaus, J R Bailey, W Slikker Jr
Comparative Study

UDP-glucuronyltransferase activity exhibits two developmental groups in liver from foetal rhesus monkeys

J E Leakey et al. Biochem J. .

Abstract

UDP-glucuronyltransferase was assayed in liver from adult rhesus monkeys and foetuses during late gestation. Activities toward 2-aminophenol, 5-hydroxytryptamine, 1-naphthol and 4-nitrophenol in the foetal liver ranged from 46 to 114% of adult values, whereas activities toward bilirubin, oestradiol and testosterone were less than 5% of adult values. This suggests that in primates UDP-glucuronyltransferase develops differentially in two clusters analogous to that in the rat.

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