UDP-glucuronyltransferase activity exhibits two developmental groups in liver from foetal rhesus monkeys
- PMID: 6414458
- PMCID: PMC1152346
- DOI: 10.1042/bj2141007
UDP-glucuronyltransferase activity exhibits two developmental groups in liver from foetal rhesus monkeys
Abstract
UDP-glucuronyltransferase was assayed in liver from adult rhesus monkeys and foetuses during late gestation. Activities toward 2-aminophenol, 5-hydroxytryptamine, 1-naphthol and 4-nitrophenol in the foetal liver ranged from 46 to 114% of adult values, whereas activities toward bilirubin, oestradiol and testosterone were less than 5% of adult values. This suggests that in primates UDP-glucuronyltransferase develops differentially in two clusters analogous to that in the rat.
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