Mathematical basis of point-area deconvolution method for determining in vivo input functions
- PMID: 641805
- DOI: 10.1002/jps.2600670524
Mathematical basis of point-area deconvolution method for determining in vivo input functions
Abstract
The point-area method for deconvolution derives a "staircase" input function which, when convolved onto the characteristic function, gives an output function coincidental with the given output data points. The area--area method for deconvolution is shown to be erroneous.
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