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. 1978 May;67(5):663-5.
doi: 10.1002/jps.2600670524.

Mathematical basis of point-area deconvolution method for determining in vivo input functions

D P Vaughan, M Dennis

Mathematical basis of point-area deconvolution method for determining in vivo input functions

D P Vaughan et al. J Pharm Sci. 1978 May.

Abstract

The point-area method for deconvolution derives a "staircase" input function which, when convolved onto the characteristic function, gives an output function coincidental with the given output data points. The area--area method for deconvolution is shown to be erroneous.

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