Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 May;67(5):679-82.
doi: 10.1002/jps.2600670529.

High-pressure liquid chromatographic analysis of melphalan in plasma

S Y Chang, D S Alberts, L R Melnick, P D Walson, S E Salmon

High-pressure liquid chromatographic analysis of melphalan in plasma

S Y Chang et al. J Pharm Sci. 1978 May.

Abstract

A new sensitive and rapid high-pressure liquid chromatographic determination of melphalan in plasma was developed. Recovery of 1 microgram added to 1 ml of plasma at 23 degrees was 94% but was greatly reduced at higher temperature. The method has been applied to plasma determinations of melphalan in rats and humans and is currently being utilized for human pharmacokinetic studies.

PubMed Disclaimer

LinkOut - more resources