Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1978 Apr;15(2):148-51.
doi: 10.1136/jmg.15.2.148.

Partial trisomy 18 in a family with a translocation (18;21)(q21;q22)

M Niazi, D V Coleman, P Saldaña-Garcia
Case Reports

Partial trisomy 18 in a family with a translocation (18;21)(q21;q22)

M Niazi et al. J Med Genet. 1978 Apr.

Abstract

A family is described in which 2 sibs had similar congenital abnormalities. Chromosome investigation of the mother and another child disclosed they were carriers of a translocation t(18;21)(q21;q22). The karyotype of one of the abnormal infants was determined and was found to be consistent with partial trisomy 18,46,XY,-21,+der (21),t(18;21) ((18pter leads to 18q21::21q22 leads to 2 lqter)mat.

PubMed Disclaimer

References

    1. Can Med Assoc J. 1962 Sep 8;87:559-61 - PubMed
    1. Exp Cell Res. 1960 Sep;20:613-6 - PubMed
    1. J Med Genet. 1976 Dec;13(6):520-2 - PubMed
    1. Lancet. 1971 Oct 30;2(7731):971-2 - PubMed
    1. Ann Genet. 1972 Mar;15(1):45-9 - PubMed

Publication types

LinkOut - more resources