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Comparative Study
. 1983 Dec;96(12):67-9.

[Correlation of the sister chromatid exchange level with chromosome aberrations induced by chemical mutagens in vivo]

[Article in Russian]
E G Shcheglova, A N Chebotarev
  • PMID: 6419793
Comparative Study

[Correlation of the sister chromatid exchange level with chromosome aberrations induced by chemical mutagens in vivo]

[Article in Russian]
E G Shcheglova et al. Biull Eksp Biol Med. 1983 Dec.

Abstract

The data on the dose dependencies of the induction of sister chromatid exchanges (SCE) and chromosomal aberrations during exposure of mouse bone marrow cells in vivo to 5 alkylating substances are provided. The efficacy of SCE induction was found to be higher than that of chromosomal aberrations. It was established that SCE induced by chemical mutagens in vivo and in vitro are more sensitive and stable tests than chromosomal aberrations.

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