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Clinical Trial
. 1983 Dec;37(6):453-8.

The effect of enteral nutritional support on skeletal muscle protein synthesis and whole-body protein turnover in fasted surgical patients

M W Ward, D Halliday, D E Matthews, S M Matthews, J L Peters, R A Harrison, C G Clark, M J Rennie
  • PMID: 6421778
Clinical Trial

The effect of enteral nutritional support on skeletal muscle protein synthesis and whole-body protein turnover in fasted surgical patients

M W Ward et al. Hum Nutr Clin Nutr. 1983 Dec.

Abstract

Whole-body and muscle protein turnover have been studied in surgical patients, before abdominal surgery after an 18-h fast, using infusion of 1-[13C]leucine. Four patients received an unmodified hospital diet and four received extra nutritional support (1800 kcal, 70 g protein) by naso-jejunal tube for 7-10 d previously. In patients who received nutritional support there were significantly greater values of whole-body protein synthesis (+42 per cent, P less than 0.05) and breakdown (+45 per cent, P less than 0.01) and muscle protein synthesis (+36 per cent, P less than 0.05) than in those who received the unmodified hospital diet.

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