Isolation, structure, and synthesis of a human seminal plasma peptide with inhibin-like activity
- PMID: 6422553
- DOI: 10.1126/science.6422553
Isolation, structure, and synthesis of a human seminal plasma peptide with inhibin-like activity
Abstract
A basic peptide isolated from pooled human seminal plasma exhibited inhibin-like activity by suppressing pituitary follicle-stimulating hormone secretion in vitro and in vivo. The peptide has been characterized and sequenced, and a 31-amino-acid synthetic replicate showed full biological activity in vitro.
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