[Demonstration of the correlation of the degree of synthesis and 4-aminobutyric acid levels in the central nervous system; effect of repeated convulsive seizures]
[Article in
French]
- PMID: 6424902
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[Demonstration of the correlation of the degree of synthesis and 4-aminobutyric acid levels in the central nervous system; effect of repeated convulsive seizures]
[Article in
French]
C R Acad Sci III.
1984.
Abstract
GABA turnover rates have been determined in 15 brain areas in five inbred strains of Mice or sublines (DBA/2J, C57/6J, Swiss Rb1, Swiss Rb2, Swiss Rb3). GABA turnover rates and levels are correlated (2 P less than 0.05). After repeated seizures (twice a day for 15 days), induced by an acoustic stimulus in Swiss Rb1 Mice selected for audiogenic seizures, this correlation is no longer observed.
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