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. 1984;59(1):81-7.
doi: 10.1007/BF01249880.

L-deprenyl plus L-phenylalanine in the treatment of depression

W Birkmayer, P Riederer, W Linauer, J Knoll

L-deprenyl plus L-phenylalanine in the treatment of depression

W Birkmayer et al. J Neural Transm. 1984.

Abstract

The antidepressive efficacy of 1-deprenyl (5-10 mg daily) plus 1-phenylalanine (250 mg/day) has been evaluated in 155 unipolar depressed patients. Both oral and intravenous administration showed beneficial effects in 90% of outpatients and 80.5% of inpatients. It is concluded that this combined treatment has a potent antidepressive action based on the accumulation of 1-phenylethylamine in the brain.

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