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. 1977 Jan 21;464(2):442-7.
doi: 10.1016/0005-2736(77)90017-7.

Raman spectroscopic investigation of the interaction of gramicidin A with dipalmitoyl phosphatidylcholine liposomes

E Weidekamm, E Bamberg, D Brdiczka, G Wildermuth, F Macco, W Lehmann, R Weber

Raman spectroscopic investigation of the interaction of gramicidin A with dipalmitoyl phosphatidylcholine liposomes

E Weidekamm et al. Biochim Biophys Acta. .

Abstract

The interaction of gramicidin A with dipalmitoyl phosphatidylcholine liposomes is investigated by Laser-Raman spectroscopy. As revealed by the methylene C-H stretching mode the phase transition of the hydrocarbon chains near 40 degree C is eliminated in the presence of gramicidin A. Liposomes prepared from a mixture of lecithin and cholesterol seem to be unaffected by gramicidin A and show only the normal broadened phase transition.

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