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. 1984;6(3):335-43.

Changes in platelet aggregation caused by glyburide in diabetic patients

  • PMID: 6426797

Changes in platelet aggregation caused by glyburide in diabetic patients

R De Bellis et al. Clin Ther. 1984.

Abstract

The effect of glyburide on platelet aggregation was investigated in 31 patients with maturity-onset diabetes. Platelet aggregation in platelet-rich plasma was measured before and one hour after the patients had ingested 5 mg of glyburide. The drug caused a significant decrease in platelet aggregation as determined by changes in the amplitude and slope of the curve.

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