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Clinical Trial
. 1984 Jun 9;288(6432):1715-6.
doi: 10.1136/bmj.288.6432.1715.

Subcutaneous terbutaline and control of brittle asthma or appreciable morning dipping

J Ayres, D R Fish, D C Wheeler, J Wiggins, G M Cochrane, C Skinner
Clinical Trial

Subcutaneous terbutaline and control of brittle asthma or appreciable morning dipping

J Ayres et al. Br Med J (Clin Res Ed). .

Abstract

In a pilot study two patients with brittle asthma and two with morning dipping received terbutaline or a placebo administered subcutaneously either by continuous infusion or in injections every six hours. In two patients brittle asthma was completely suppressed by terbutaline 1 mg/day given by either method. In the two others early morning dipping responded only to continuous subcutaneous infusions of terbutaline 12 mg/day. Terbutaline administered subcutaneously may be an effective treatment in asthmatic patients who show important diurnal variations in air flow.

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