Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Feb 28;4(1):25-8.
doi: 10.1007/BF00775176.

Phospholipid composition of human erythrocyte spectrin

E Weidekamm, B Brdiczka, M Wildermuth

Phospholipid composition of human erythrocyte spectrin

E Weidekamm et al. Mol Biol Rep. .

Abstract

Human erythrocyte spectrin, which has been extracted at low ionic strength and precipitated at pH 5.1, contains 0.025 mumoles phospholipid/mg protein. The composition of the spectrin-phospholipids differs from that of the erythrocyte membrane. A remarkable similarity was found between the composition of the "available" phospholipids of the inner leaflet of the membrane bilayer and the spectrin-associated phospholipids. Rebinding studies with 125I-labeled spectrin show that the labeled spectrin binds preferentially to the cytoplasmic side of the membrane and that this binding is influenced by protein perturbations.

PubMed Disclaimer

References

    1. Biochem Biophys Res Commun. 1971 Nov;45(4):1063-70 - PubMed
    1. Biochim Biophys Acta. 1973 Apr 25;307(1):65-73 - PubMed
    1. Naturwissenschaften. 1971 Apr;58(4):220 - PubMed
    1. Biochemistry. 1971 Jun 22;10(13):2606-17 - PubMed
    1. Biochem Biophys Res Commun. 1970 Oct 9;41(1):135-41 - PubMed