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. 1978 May 18;273(5659):203-8.
doi: 10.1038/273203a0.

Nucleotide sequence and secondary structure of potato spindle tuber viroid

H J Gross, H Domdey, C Lossow, P Jank, M Raba, H Alberty, H L Sänger

Nucleotide sequence and secondary structure of potato spindle tuber viroid

H J Gross et al. Nature. .

Abstract

The viroid of the potato spindle tuber disease (PSTV) is a covalently closed ring of 359 ribonucleotides. As a result of intramolecular base pairing, a serial arrangement of double-helical sections and internal loops form a unique rod-like secondary structure. PSTV is the first pathogen of a eukaryotic organism for which the complete molecular structure has been established.

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