Biological correlates of attachment bond disruption in humans and nonhuman primates
- PMID: 6435181
Biological correlates of attachment bond disruption in humans and nonhuman primates
Abstract
Separations or disruptions in attachment bonds occur frequently in the social lives of humans and have been linked to the development of psychopathology. Separation of social nonhuman primates has been proposed as a model to study the psychological and biological effects of separation in humans. This paper reviews the biological alterations that occur in nonhuman primates undergoing separation and compares these with changes associated with separation in humans. The data reviewed demonstrate that separation in humans and nonhuman primates can be an event with profound behavioral and physiological sequelae.
Similar articles
-
Primate models of separation-induced depression.Psychiatr Clin North Am. 1987 Sep;10(3):437-47. Psychiatr Clin North Am. 1987. PMID: 3120161 Review.
-
Urinary free cortisol and separation anxiety early in the course of bereavement and threatened loss.Biol Psychiatry. 1987 Feb;22(2):148-52. doi: 10.1016/0006-3223(87)90225-3. Biol Psychiatry. 1987. PMID: 3814667
-
Social buffering of stress responses in nonhuman primates: Maternal regulation of the development of emotional regulatory brain circuits.Soc Neurosci. 2015;10(5):512-26. doi: 10.1080/17470919.2015.1087426. Epub 2015 Sep 17. Soc Neurosci. 2015. PMID: 26324227 Free PMC article. Review.
-
The impact of early adverse care on HPA axis development: nonhuman primate models.Horm Behav. 2006 Nov;50(4):623-31. doi: 10.1016/j.yhbeh.2006.06.012. Epub 2006 Aug 15. Horm Behav. 2006. PMID: 16914153 Review.
-
Psychological and physiological responses to stress: the right hemisphere and the hypothalamo-pituitary-adrenal axis, an inquiry into problems of human bonding.Acta Physiol Scand Suppl. 1997;640:10-25. Acta Physiol Scand Suppl. 1997. PMID: 9401599 Review.
Cited by
-
New policies on skin-to-skin contact warrant an oxytocin-based perspective on perinatal health care.Front Psychol. 2024 Jul 9;15:1385320. doi: 10.3389/fpsyg.2024.1385320. eCollection 2024. Front Psychol. 2024. PMID: 39049943 Free PMC article.
-
Invasive Research on Non-Human Primates-Time to Turn the Page.Animals (Basel). 2021 Oct 19;11(10):2999. doi: 10.3390/ani11102999. Animals (Basel). 2021. PMID: 34680019 Free PMC article.
-
Anterior hippocampal volume is reduced in behaviorally depressed female cynomolgus macaques.Psychoneuroendocrinology. 2009 Nov;34(10):1469-75. doi: 10.1016/j.psyneuen.2009.04.022. Epub 2009 Jun 2. Psychoneuroendocrinology. 2009. PMID: 19493628 Free PMC article.
-
Neuropeptide expression in rats exposed to chronic mild stresses.Psychopharmacology (Berl). 2005 Mar;178(2-3):115-24. doi: 10.1007/s00213-004-2015-3. Epub 2004 Oct 30. Psychopharmacology (Berl). 2005. PMID: 15719227
-
Cell number and neuropil alterations in subregions of the anterior hippocampus in a female monkey model of depression.Biol Psychiatry. 2013 Dec 15;74(12):890-7. doi: 10.1016/j.biopsych.2013.03.013. Epub 2013 Apr 19. Biol Psychiatry. 2013. PMID: 23607969 Free PMC article.