doi: 10.1126/science.6435246.
Chromosomal location of human T-cell receptor gene Ti beta
- PMID: 6435246
- DOI: 10.1126/science.6435246
Item in Clipboard
Chromosomal location of human T-cell receptor gene Ti beta
Science.
.
Abstract
A complementary DNA probe corresponding to the beta-chain gene of Ti, the human T lymphocyte receptor, has been molecularly cloned. The chromosomal origin of the Ti beta gene was determined with the complementary DNA by screening a series of 12 cell hybrid (mouse X human) DNA's containing overlapping subsets of human chromosomes. DNA hybridization (Southern) experiments showed that the human Ti beta gene resides on chromosome 7 and is thus not linked to the immunoglobulin loci or to the major histocompatibility locus in humans.
Similar articles
-
Regional location of T cell receptor gene Ti alpha on human chromosome 14.J Exp Med. 1985 Jul 1;162(1):387-92. doi: 10.1084/jem.162.1.387. J Exp Med. 1985. PMID: 3925071 Free PMC article.
-
The gene encoding the T-cell receptor alpha-chain maps close to the Np-2 locus on mouse chromosome 14.Nature. 1985 Mar 21-27;314(6008):271-3. doi: 10.1038/314271a0. Nature. 1985. PMID: 3920527
-
The human T-cell receptor alpha-chain gene maps to chromosome 14.Nature. 1985 Mar 21-27;314(6008):273-4. doi: 10.1038/314273a0. Nature. 1985. PMID: 3838574
-
Molecular genetic analysis of the V kappa Ser group associated with two mouse light chain genetic markers. Complementary DNA cloning and southern hybridization analysis.J Exp Med. 1985 Aug 1;162(2):713-28. doi: 10.1084/jem.162.2.713. J Exp Med. 1985. PMID: 3926938 Free PMC article. Review.
-
Genes encoding the alpha, beta, and gamma chains of the human T cell antigen receptor.J Infect Dis. 1987 Mar;155(3):418-22. doi: 10.1093/infdis/155.3.418. J Infect Dis. 1987. PMID: 3543154 Review. No abstract available.
Cited by
-
The genes for CD37, CD53, and R2, all members of a novel gene family, are located on different chromosomes.Immunogenetics. 1993;37(6):461-5. doi: 10.1007/BF00222471. Immunogenetics. 1993. PMID: 8436422
-
Comparative map for mice and humans.Mamm Genome. 1991;1 Spec No:S461-515. doi: 10.1007/BF00656504. Mamm Genome. 1991. PMID: 1799811 Review. No abstract available.
-
Human chromosome 7 carries the beta 2 interferon gene.Proc Natl Acad Sci U S A. 1986 Jul;83(14):5219-22. doi: 10.1073/pnas.83.14.5219. Proc Natl Acad Sci U S A. 1986. PMID: 3014537 Free PMC article.
-
Cognate homeo-box loci mapped on homologous human and mouse chromosomes.Proc Natl Acad Sci U S A. 1986 Dec;83(23):9104-8. doi: 10.1073/pnas.83.23.9104. Proc Natl Acad Sci U S A. 1986. PMID: 2878432 Free PMC article.
-
Segregation of polymorphic T-cell receptor genes in human families.Proc Natl Acad Sci U S A. 1985 Jun;82(11):3804-8. doi: 10.1073/pnas.82.11.3804. Proc Natl Acad Sci U S A. 1985. PMID: 2987947 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
Molecular Biology Databases
