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. 1984;43(8-9):S222-6.

Formation of lipoxygenase and cyclooxygenase metabolites of arachidonic acid by brain tissue

A Dembińska-Kieć, R Korbut, A Zmuda, E Kostka-Trabka, T Simmet, B A Peskar
  • PMID: 6440538

Formation of lipoxygenase and cyclooxygenase metabolites of arachidonic acid by brain tissue

A Dembińska-Kieć et al. Biomed Biochim Acta. 1984.

Abstract

Rat brain slices released spontaneously and after challenge with A23187 LTC4-like radioimmunoactivity. Total cat brain ischemia followed by short postischemic reperfusion period resulted in the increased release of lipid peroxides and PGE2 but not in LTC4-like substance by brain slices. In lumbar cerebrospinal fluid of patients with completed stroke presence of LTC4-like material was observed.

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