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. 1980 Feb;141(2):464-9.
doi: 10.1128/jb.141.2.464-469.1980.

Suppression of induction of SOS functions in an Escherichia coli tif-1 mutant by plasmid R100.1

M Bagdasarian, R D'Ari, W Filipowicz, J George

Suppression of induction of SOS functions in an Escherichia coli tif-1 mutant by plasmid R100.1

M Bagdasarian et al. J Bacteriol. 1980 Feb.

Abstract

The tif-1 mutation in the recA gene of Escherichia coli caused, at 40 degrees C, lethal cell filamentation, induction of the recA protein, mutagenesis, and, in lambda lysogens, prophage induction. The presence of plasmid R100.1 in tif-1 strains suppressed tif-mediated cell filamentation and killing, recA protein induction, and prophage induction in lysogens. It also reduced mutagenesis in a tif-1 sfiA11(R100.1) strain. Plasmids F'lac, P1, and pMB9, in contrast, had little or no effect on tif-mediated induction of lambda. The presence of R100.1 did not inhibit the induction of the recA protein or of lambda by ultraviolet irradiation or mitomycin C treatment of tif-1(R100.1) or tif-1(lambda)(R100.1) strains.

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References

    1. J Gen Microbiol. 1965 Jul;40(1):43-55 - PubMed
    1. Mutat Res. 1966 Apr;3(2):129-34 - PubMed
    1. Radiat Res. 1966;:Suppl 6:156+ - PubMed
    1. Virology. 1968 Dec;36(4):564-74 - PubMed
    1. Cold Spring Harb Symp Quant Biol. 1968;33:785-9 - PubMed

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