Isometric tensions developed during the hydrothermal swelling of rat skin

Abstract

Isometric tensions developed in connective tissue under the influence of temperature have previously been measured by their effect on a "shrinkage" phenomenon observed along the main axis of the collagen fibers. A new device, built and tested in our laboratory enabled us to obtain isometric tension curves by measuring a "swelling" phenomenon observed in other directions. Curves recorded in the two systems have been compared. Shapes were unchanged and the parameters chosen to define these morphologies showed the same values in both types of experiments. The parameters, which are independent of maximal tension, were also found to be independent of the total collagen content of the sample. Interpretation of the results suggests that these parameters depend not only on the nature but also on the density of the collagen crosslinks. The new device is applicable to minute tissue samples, whatever their fragility and fiber orientation.