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Comparative Study
. 1980 Sep 15;36(9):1092-4.
doi: 10.1007/BF01965988.

Serotoninergic modulation of mesolimbic and frontal cortical dopamine neurons

P C Waldmeier
Comparative Study

Serotoninergic modulation of mesolimbic and frontal cortical dopamine neurons

P C Waldmeier. Experientia. .

Abstract

Potentiation of the effect of haloperidol on dopamine metabolism by the 5-HT uptake inhibitor CGP 6085 A, and antagonism of this effect by the 5-HT antagonist mianserin were observed in the mesolimbic area and the frontal cortex of the rat brain. A similar effect was reported earlier in the corpus striatum. This suggests that serotoninergic modulation of dopamine neurons is a generally-occurring phenomenon in the brain.

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References

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