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. 1981 Jan 10;1(1):35-6.
doi: 10.5694/j.1326-5377.1981.tb135286.x.

Pharmacokinetics of piperacillin in renal failure

C R George, J Burgoyne, G R Funnell, P Robinson, P Collignon, K Meads, M D Guinness

Pharmacokinetics of piperacillin in renal failure

C R George et al. Med J Aust. .

Abstract

Patients with chronic renal failure who received bolus doses of piperacillin maintained high serum levels for up to six hours. The percentage of the injected dose which was detectable in the urine in 24 hours was reduced proportionately to the severity of the renal failure.

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