Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1981 Jul;33(4):629-39.

Mortality and survival for Down syndrome in Japan

M Masaki, M Higurashi, K Iijima, N Ishikawa, F Tanaka, T Fujii, Y Kuroki, I Matsui, K Iinuma, N Matsuo, K Takeshita, S Hashimoto
Comparative Study

Mortality and survival for Down syndrome in Japan

M Masaki et al. Am J Hum Genet. 1981 Jul.

Abstract

Mortality and survival data for 1,052 Japanese patients with Down syndrome who were born between 1966 and 1975 were analyzed. The survival rate at age 10 was estimated to be about 86%. Mortality in each age group for Down syndrome was elevated over that of the general population. In the survival rate at age 10, there was no significant difference between males and females, but the difference between cases with and without congenital heart disease was highly significant. Using data from this study-for mortality up to age 10-and from the study of institutionalized cases for mortality over age 10, a hypothetical life table was constructed; it shows that the life expectancy at birth for cases with Down syndrome is nearly 50 years.

PubMed Disclaimer

References

    1. Early Hum Dev. 1979 Mar;3(1):29-41 - PubMed
    1. J Ment Defic Res. 1975 Sep-Dec;19(3-4):157-63 - PubMed
    1. J Ment Defic Res. 1963 Jun;7:60-8 - PubMed
    1. J Ment Defic Res. 1970 Sep;14(3):235-42 - PubMed
    1. Br J Prev Soc Med. 1955 Jan;9(1):10-5 - PubMed

Publication types

LinkOut - more resources