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Clinical Trial
. 1981 May;56(5):342-4.
doi: 10.1136/adc.56.5.342.

Bronchodilator effects of clemastine, ipratropium, bromide, and salbutamol in preschool children with asthma

R C Groggins, A D Milner, G M Stokes
Clinical Trial

Bronchodilator effects of clemastine, ipratropium, bromide, and salbutamol in preschool children with asthma

R C Groggins et al. Arch Dis Child. 1981 May.

Abstract

The bronchodilator activity in nebulised salbutamol, ipratropium bromide, clemastine, and a placebo was studied in 14 asthmatic children aged between 3 and 5 years. Changes in lung function were monitored by measuring peak expiratory flow rate and total respiratory resistance using a modification of the forced oscillation technique. Ipratropium bromide produced a degree of bronchodilation similar to that of salbutamol, but the bronchodilatory activity of clemastine was not appreciably better than for the placebo.

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