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. 1981;37(8):807-9.
doi: 10.1007/BF01985651.

The serum levels of unbound bilirubin that induce changes in some brain mitochondrial reactions in newborn guinea-pigs

M A Almeida, L Rezende Jr

The serum levels of unbound bilirubin that induce changes in some brain mitochondrial reactions in newborn guinea-pigs

M A Almeida et al. Experientia. 1981.

Abstract

Bilirubin in different concentrations was injected in newborn guinea-pigs and the following parameters were determined: serum total and unbound bilirubin, whole brain bilirubin content and oxygen consumption, NADH-cytochrome c reductase and ATPase activities in brain mitochondria. The results showed a significant correlation between decreased rates of brain metabolism and the elevation of serum total and unbound bilirubin.

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