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Comparative Study
. 1981 May-Jun;132(3):267-81.

[Structure-activity relationships in the quinolone group: antibacterial activity of two new compounds (author's transl)]

[Article in French]
M Thibault, B Koumaré, C J Soussy, J Duval
  • PMID: 6457546
Comparative Study

[Structure-activity relationships in the quinolone group: antibacterial activity of two new compounds (author's transl)]

[Article in French]
M Thibault et al. Ann Microbiol (Paris). 1981 May-Jun.

Abstract

Authors describe structure-activity relationships in quinolone group and report a study of the antibacterial activity of two new compounds: pefloxacin and its demethyl derivative, AM-715. These two products take place in the field of researches carried out for extending indications of this group of antimicrobial agents by obtaining derivatives more active, with broader spectrum, less biotransformed and susceptible to be used in general infections and not only in urinary tract infections.

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