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Clinical Trial
. 1982 Jan;69(1 Pt 1):60-5.
doi: 10.1016/0091-6749(82)90089-6.

Combination bronchodilator therapy in asthma

Clinical Trial

Combination bronchodilator therapy in asthma

R E Ruffin et al. J Allergy Clin Immunol. 1982 Jan.

Abstract

This study has compared the short-term bronchodilator effects of inhaled anticholinergic (ipratropium bromide) and sympathomimetic (fenoterol) agents alone and in combination in 18 asthmatic patients. the study was of double-blind, placebo-controlled, crossover design. The combination of 60 micrograms ipratropium bromide and 200 micrograms of fenoterol had a greater bronchodilator effect than lower dose combinations or either drug alone. Small but significant gains may be made with combination inhaled bronchodilator therapy.

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