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Comparative Study
. 1984 Jul;39(7):500-4.
doi: 10.1136/thx.39.7.500.

Comparative effects of inhaled leukotriene C4, leukotriene D4, and histamine in normal human subjects

N C Barnes, P J Piper, J F Costello
Comparative Study

Comparative effects of inhaled leukotriene C4, leukotriene D4, and histamine in normal human subjects

N C Barnes et al. Thorax. 1984 Jul.

Abstract

The comparative actions of inhaled leukotriene C4 (LTC4), leukotriene D4 (LTD4), and histamine were studied in six normal subjects. LTC4 and LTD4 were shown to be more potent bronchoconstrictors than histamine, with a more sustained action. LTC4 and LTD4 caused wheezing without cough or throat irritation and were shown to act on large and small airways.

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References

    1. JAMA. 1983 May 27;249(20):2814-7 - PubMed
    1. N Engl J Med. 1983 Feb 24;308(8):436-9 - PubMed
    1. J Appl Physiol. 1967 Jan;22(1):95-108 - PubMed
    1. J Clin Invest. 1969 Jun;48(6):1159-68 - PubMed
    1. Br J Dis Chest. 1971 Jul;65:135-69 - PubMed

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