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Case Reports
. 1984 Aug;49(2):107-9.
doi: 10.1007/BF00363702.

Castleman's disease with coagulation defect. A case report

S C Rizzo, C L Balduini, G Gamba, R Invernizzi, G Grignani, C Mauri
Case Reports

Castleman's disease with coagulation defect. A case report

S C Rizzo et al. Blut. 1984 Aug.

Abstract

The case of a young man with the plasma cell type of Castleman's disease is described. Beyond the well known systemic manifestations the coagulation tests showed a decrease in the activity of factors V, VIII and X due to the presence of lupus-like circulating anticoagulants. After surgical excision of the mediastinal mass both hematochemical pathological data and the coagulation defect disappeared. It is suggested that the lupus-like anticoagulant was secreted by the tumor.

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