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. 1984 Aug 15;40(8):852-4.
doi: 10.1007/BF01951991.

Light dependent accumulation of macrophages at the photoreceptor-pigment epithelial interface in the retina of albino mice

S Sanyal, A De Ruiter, C Dees

Light dependent accumulation of macrophages at the photoreceptor-pigment epithelial interface in the retina of albino mice

S Sanyal et al. Experientia. .

Abstract

In the subretinal space of albino mice, macrophages appear from the time of eye opening and increase in number for 6 months; thereafter they decline with age. Dark rearing retards the accumulation of these cells, and exposure to constant light results in a rapid increase. Observations suggest that macrophages appear as a response to visual cell decay in albino mice and supplement the phagocytic activity of the pigment epithelium.

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