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Comparative Study
. 1984;80(6):563-7.

Localization of filipin-sterol complexes in cell membranes of eosinophils

P F Pimenta, W de Souza
  • PMID: 6469713
Comparative Study

Localization of filipin-sterol complexes in cell membranes of eosinophils

P F Pimenta et al. Histochemistry. 1984.

Abstract

The polyene antibiotic filipin was used as a probe for the detection of cholesterol in the cell membranes of eosinophils isolated from the peritoneal exudate of rats. A homogenous distribution of filipin-sterol complexes was observed, both in thin sections and freeze-fracture replicas throughout the whole plasma membrane but not in the membrane of pynocytic vesicles, Golgi complex, endoplasmic reticulum, mitochondria and the nucleus. Few complexes were seen in freeze-fracture replicas showing the membrane of the specific granules. Treatment of living cells with filipin induced aggregation of filipin-sterol complexes at some points of the plasma membrane.

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References

    1. Biochim Biophys Acta. 1973 Jan 26;291(2):577-81 - PubMed
    1. Lipids. 1978 Oct;13(10):686-91 - PubMed
    1. J Exp Med. 1975 Oct 1;142(4):805-13 - PubMed
    1. J Histochem Cytochem. 1979 Sep;27(9):1247-60 - PubMed
    1. Int Rev Cytol. 1979;60:121-47 - PubMed

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