Transient heterosynaptic depression in the hippocampal slice
- PMID: 647417
- DOI: 10.1016/0361-9230(78)90045-x
Transient heterosynaptic depression in the hippocampal slice
Abstract
Two independent, excitatory, monosynaptic afferent fiber systems projecting onto basal and apical dendritic layers of the CA1 sub-field of the hippocampus were tested for interactive effects. Long-term potentiation of either of the pathways was accompanied by a transient depression in the other pathway. Similar transient depression could be elicited by antidromic stimulation of the CA1 cells. No long-term heterosynaptic effects were observed.
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