[Synaptic plasticity of the human cerebral cortex in hypoxia (a morphometric study)]

Abstract

Using morphometric methods, the synaptic architectonics of the neocortex molecular layer was studied in nine patients with brain tumours and intracranial hypertension of various severity which determined the degree of cerebral hypoxia. It has been demonstrated that the synapses of the human brain are characterized by marked plastic properties manifested predominantly by the hypertrophy of the active zones of the contact and the formation of the interneuronal links. The reorganization of the synaptic architectonics plays a significant compensatory role in human cerebral functions under hypoxia.