G, A and M immunoglobulin levels in parturient's blood serum, umbilical blood of their neonates and the amniotic fluid in physiological deliveries

Abstract

The present investigation is aimed at determination of G, A and M immunoglobulins concentration levels in the blood serum of parturients, umbilical blood of their neonates and in the amniotic fluid in 50 women with physiological pregnancy and delivery whose neonates were fully mature. In order to evaluate IgG, IgA and IgM concentration in the biological fluids, the method of inhibition of passive hemagglutination was applied. IgG and IgA were detected in all the three environments, while the presence of IgM was confirmed in all cases in the blood serum but only in 78% of the tested samples of the aminotic fluid. Mean values of IgG and IgM concentration both in the parturients' serum as well as in the umbilical blood of their neonates as compared with the values found in the amniotic fluid, revealed statistically significant differences. The statistically significant correlation noted between the values of IgG concentration in the parturients' serum and the umbilical blood of their neonates was not confirmed in the case of IgA and IgM.