Human placenta beta-galactoside-binding lectin. Purification and some properties
- PMID: 6477573
- DOI: 10.1016/0006-291x(84)91181-1
Human placenta beta-galactoside-binding lectin. Purification and some properties
Abstract
A beta-galactoside-binding lectin was extracted from human placenta homogenate with lactose solution and purified to apparent homogeneity by affinity chromatography on asialofetuin-Sepharose. The apparent subunit molecular weight of the lectin was 13,800 and its isoelectric point was about 5. Several saccharides containing D-galactose inhibited the hemagglutinating activity. The lectin resembles other vertebrate beta-galactoside-binding lectins in various biochemical characteristics.
Similar articles
-
Purification and characterization of beta-galactoside-binding lectin from chick embryonic skin.Biochim Biophys Acta. 1983 Dec 27;761(3):237-45. doi: 10.1016/0304-4165(83)90071-5. Biochim Biophys Acta. 1983. PMID: 6197094
-
Purification and characterization of a galactoside-binding lectin from human brain.Arch Biochem Biophys. 1989 Mar;269(2):433-9. doi: 10.1016/0003-9861(89)90127-6. Arch Biochem Biophys. 1989. PMID: 2919877
-
Purification and characterization of a lectin from seeds of the winged bean, Psophocarpus tetragonolobus (L.)DC.Biochim Biophys Acta. 1979 Nov 23;581(1):63-70. doi: 10.1016/0005-2795(79)90221-6. Biochim Biophys Acta. 1979. PMID: 508795
-
Physical and chemical characterization of the major lactose-blockable lectin activity from fetal calf skeletal muscle.Biochim Biophys Acta. 1981 Aug 28;670(1):110-23. doi: 10.1016/0005-2795(81)90055-6. Biochim Biophys Acta. 1981. PMID: 7272325
-
Affinity chromatography of macromolecular substances on adsorbents bearing carbohydrate ligands.Adv Carbohydr Chem Biochem. 1981;39:405-47. doi: 10.1016/s0065-2318(08)60210-3. Adv Carbohydr Chem Biochem. 1981. PMID: 7025595 Review. No abstract available.
Cited by
-
Binding of galectin-1 (gal-1) to the Thomsen-Friedenreich (TF) antigen on trophoblast cells and inhibition of proliferation of trophoblast tumor cells in vitro by gal-1 or an anti-TF antibody.Histochem Cell Biol. 2006 Oct;126(4):437-44. doi: 10.1007/s00418-006-0178-1. Epub 2006 Apr 11. Histochem Cell Biol. 2006. PMID: 16607538
-
Galectin-1 induced activation of the apoptotic death-receptor pathway in human Jurkat T lymphocytes.Histochem Cell Biol. 2008 May;129(5):599-609. doi: 10.1007/s00418-008-0395-x. Epub 2008 Feb 21. Histochem Cell Biol. 2008. PMID: 18288482
-
Further evidence by site-directed mutagenesis that conserved hydrophilic residues form a carbohydrate-binding site of human galectin-1.Glycoconj J. 1994 Oct;11(5):437-42. doi: 10.1007/BF00731280. Glycoconj J. 1994. PMID: 7535135
-
Anti-galectin-1 autoantibodies in human Trypanosoma cruzi infection: differential expression of this beta-galactoside-binding protein in cardiac Chagas' disease.Clin Exp Immunol. 2001 May;124(2):266-73. doi: 10.1046/j.1365-2249.2001.01512.x. Clin Exp Immunol. 2001. PMID: 11422204 Free PMC article.
-
Severe preeclampsia is characterized by increased placental expression of galectin-1.J Matern Fetal Neonatal Med. 2008 Jul;21(7):429-42. doi: 10.1080/14767050802041961. J Matern Fetal Neonatal Med. 2008. PMID: 18570123 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources