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Clinical Trial
. 1984 Aug;26(2):200-3.
doi: 10.1128/AAC.26.2.200.

Treatment of influenza A (H1N1) virus infection with ribavirin aerosol

S Z Wilson, B E Gilbert, J M Quarles, V Knight, H W McClung, R V Moore, R B Couch
Clinical Trial

Treatment of influenza A (H1N1) virus infection with ribavirin aerosol

S Z Wilson et al. Antimicrob Agents Chemother. 1984 Aug.

Abstract

In a randomized, controlled study of ribavirin aerosol treatment of influenza A(H1N1) virus infection among college students, treated patients had a significantly shorter duration of fever than control patients. There was a trend of more rapid recovery in treated patients. Virus shedding was similar in treated and control patients, declining gradually from a 50% tissue culture infective dose of 3.5 log10 per ml at admission to 1.8 log10 per ml at 53 h after admission. There was no local or systemic intolerance and no hematological or biochemical abnormalities associated with ribavirin treatment.

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References

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