doi: 10.1007/BF00291623.
Cytogenetic study in spermatocytes of mice and Chinese hamsters after treatment with isoniazid (INH)
- PMID: 649168
- DOI: 10.1007/BF00291623
Item in Clipboard
Cytogenetic study in spermatocytes of mice and Chinese hamsters after treatment with isoniazid (INH)
Hum Genet.
.
Abstract
Meiotic chromosomes of spermatocytes from INH-treated male mice and Chinese hamsters were analysed for chromosome aberrations in diakinesis-metaphase I and metaphase II. The experiments were performed in two laboratories while a third laboratory participated in the chromosome evaluation. No enhancement of chromosome aberrations could be observed after acute treatment of early primary spermatocytes or chronic treatment of spermatogonia with INH.
Similar articles
-
The effect of isoniazid (INH) on Chinese hamster and mouse spermatogonia.Hum Genet. 1978 May 16;42(1):44-9. doi: 10.1007/BF00291622. Hum Genet. 1978. PMID: 649167
-
Cytogenetic effects induced by organophosphorus pesticides in mouse spermatocytes.Toxicol Lett. 1984 Jun;21(3):315-9. doi: 10.1016/0378-4274(84)90090-0. Toxicol Lett. 1984. PMID: 6740720
-
[Chromosome aberrations induced by cyclophosphamide in the meiotic cells of male mice].Tsitol Genet. 1980 Jul-Aug;14(4):29-35. Tsitol Genet. 1980. PMID: 7192444 Russian.
-
Delayed formation of chromosome aberrations in mouse pachytene spermatocytes treated with triethylenemelamine (TEM).Genetics. 1977 Jan;85(1):65-72. doi: 10.1093/genetics/85.1.65. Genetics. 1977. PMID: 838271 Free PMC article.
-
Chromosome analysis of bone marrow in mammals after treatment with isoniazid.Hum Genet. 1978 May 16;42(1):15-25. doi: 10.1007/BF00291618. Hum Genet. 1978. PMID: 649162
Cited by
-
Incidence of chromosomal aberrations in patients under combined tuberculostatic chemotherapy.Hum Genet. 1983;63(2):191-2. doi: 10.1007/BF00291544. Hum Genet. 1983. PMID: 6840764
-
Chromosome-damaging action of isoniazid and thiacetazone on human lymphocyte cultures in vivo.Hum Genet. 1981;57(3):321-2. doi: 10.1007/BF00278953. Hum Genet. 1981. PMID: 6166532
-
Combined action of isoniazid and para-aminosalicylic acid in vivo on human chromosomes in lymphocyte cultures.Hum Genet. 1981;56(3):375-7. doi: 10.1007/BF00274696. Hum Genet. 1981. PMID: 7239520
-
Cytogenetic effects of chemotherapy with three combinations of anti-tubercular drugs involving isoniazid, thiacetazone, para-aminosalicylic acid and streptomycin on human lymphocytes: chromosome aberrations, sister chromatid exchanges and mitotic index.Hum Genet. 1983;64(1):42-9. doi: 10.1007/BF00289477. Hum Genet. 1983. PMID: 6192073