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. 1978 May 16;42(1):50-4.
doi: 10.1007/BF00291623.

Cytogenetic study in spermatocytes of mice and Chinese hamsters after treatment with isoniazid (INH)

I D Adler, A Schmaltz, R Rathenberg, D Müller, F F Strasser, R Perret

Cytogenetic study in spermatocytes of mice and Chinese hamsters after treatment with isoniazid (INH)

I D Adler et al. Hum Genet. .

Abstract

Meiotic chromosomes of spermatocytes from INH-treated male mice and Chinese hamsters were analysed for chromosome aberrations in diakinesis-metaphase I and metaphase II. The experiments were performed in two laboratories while a third laboratory participated in the chromosome evaluation. No enhancement of chromosome aberrations could be observed after acute treatment of early primary spermatocytes or chronic treatment of spermatogonia with INH.

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