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. 1984 Dec 5;778(2):379-84.
doi: 10.1016/0005-2736(84)90382-1.

Anion exchange in human erythrocytes has a large activation volume

V A Canfield, R I Macey

Anion exchange in human erythrocytes has a large activation volume

V A Canfield et al. Biochim Biophys Acta. .

Abstract

Sulfate equilibrium exchange in human red cells has an activation volume of +150 +/- 20 cm3/mol over the pressure range 0.1 to 83 MPa (15 to 12000 lb/in2) at 30 degrees C. This value greatly exceeds the expected contribution from sulfate binding to the anion exchanger. We suggest that the activation volume reflects conformational changes during the transport cycle.

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