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. 1984 Nov;46(2):615-8.
doi: 10.1128/iai.46.2.615-618.1984.

Primary sequence of the alpha-toxin gene from Staphylococcus aureus wood 46

G S Gray, M Kehoe

Primary sequence of the alpha-toxin gene from Staphylococcus aureus wood 46

G S Gray et al. Infect Immun. 1984 Nov.

Abstract

The complete DNA sequence of a cloned alpha-toxin gene from Staphylococcus aureus was determined. The amino acid sequence of the alpha-toxin protein, predicted from the DNA sequence, was described and compared with published data. The primary product of the cloned alpha-toxin gene contained a 26-amino-acid leader sequence which possessed characteristic features of a signal sequence involved in secretion. The mature alpha-toxin protein had a molecular size of 33,000 and contained only three short regions of high hydrophobicity in addition to a number of short, weakly hydrophobic regions.

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References

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