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. 1978;42(2):159-62.
doi: 10.1007/BF01675355.

Increased effect of apomorphine on homovanillic acid in rats terminated from chronic haloperidol

R C Smith, N Narasimhachari, J M Davis

Increased effect of apomorphine on homovanillic acid in rats terminated from chronic haloperidol

R C Smith et al. J Neural Transm. 1978.

Abstract

Rats who were administered apomorphine seven days after termination of chronic treatment with haloperidol had significantly (59%) lower level of brain HVA than saline control rats. This finding is consistent with the behavioral evidence suggesting supersensitivity of post-synaptic dopamine receptors after termination of chronic haloperidol.

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