Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1976 Nov;8(5):317-26.
doi: 10.1111/j.1399-0039.1976.tb00583.x.

HLA restriction of non-HLA--A, --B, --C and --D cell mediated lympholysis (CML)

E Goulmy, A Termijtelen, B A Bradley, J J van Rood

HLA restriction of non-HLA--A, --B, --C and --D cell mediated lympholysis (CML)

E Goulmy et al. Tissue Antigens. 1976 Nov.

Abstract

The aim of our study was to define target determinants other than those coded for by the classical HLA-A, -B, -C or -D loci which were responsible for killing in CML. In one of the families studied, strong evidence was found for the existence of a determinant coded for within the HLA region. CML was restricted to targets carrying the classical HLA-Bw35 and Cw4 determinants but the targets were neither HLA-Bw35 nor Cw4 themselves. We therefore concluded that this new HLA determinant was either the product of a new locus closely associated with HLA-B or that it was a product of the classical HLA-B locus which has not been recognized by serology.

PubMed Disclaimer

LinkOut - more resources