Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1984 Jul;4(7):1416-9.
doi: 10.1128/mcb.4.7.1416-1419.1984.

Conformation takes precedence over sequence in adeno-associated virus DNA replication

R B Lefebvre, S Riva, K I Berns

Conformation takes precedence over sequence in adeno-associated virus DNA replication

R B Lefebvre et al. Mol Cell Biol. 1984 Jul.

Abstract

Deletion of an 11-base symmetrical sequence in the inverted terminal repetition of the adeno-associated virus 2 genome inhibits DNA replication. Substitution of either an 8- or a 12-base symmetrical sequence unrelated to the original 11-base sequence restores DNA replication.

PubMed Disclaimer

References

    1. J Virol. 1983 Feb;45(2):555-64 - PubMed
    1. Cell. 1983 May;33(1):135-43 - PubMed
    1. Virology. 1977 May 15;78(2):488-99 - PubMed
    1. J Virol. 1977 Nov;24(2):627-34 - PubMed
    1. Gene. 1976;1(1):81-92 - PubMed

Publication types

Associated data

LinkOut - more resources