Treatment of hypertension in mild asthmatic patients with atenolol
- PMID: 6507943
- DOI: 10.1177/000331978403501204
Treatment of hypertension in mild asthmatic patients with atenolol
Abstract
Fourteen patients with uncomplicated essential hypertension and mild asthma were treated with Atenolol 50-125 mg/day for up to 8 months. Heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP), rate pressure index (RPI), stress testing time (STT) and peak expiratory flow rate (PEFR) were measured before, during and after stress testing (ST) before and during treatment. Atenolol significantly lowered HR, SBP, DBP and RPI. It prolonged STT and had no effect on PEFR. Furthermore, Atenolol did not worsen the patient's asthma except for one patient. The drug did not interfere with the bronchodilatation effect of salbutamol. Atenolol can be used cautiously to treat hypertension in asthmatic patients under certain conditions.
Similar articles
-
The cardioselective and hypotensive effects of bisoprolol in hypertensive asthmatics.J Cardiovasc Pharmacol. 1986;8 Suppl 11:S74-7. doi: 10.1097/00005344-198511001-00013. J Cardiovasc Pharmacol. 1986. PMID: 2439803 Clinical Trial.
-
[Effectiveness of atenolol in moderate arterial hypertension. Evaluation by stress test].Rev Med Univ Navarra. 1987 Jan-Mar;31(1):23-8. Rev Med Univ Navarra. 1987. PMID: 3616360 Spanish.
-
Analysis of left ventricular function by radionuclide ventriculogram in hypertensive patients treated with atenolol.Medicina (B Aires). 1990;50(6):518-20. Medicina (B Aires). 1990. PMID: 2130241
-
Osmotic release oral drug delivery system of metoprolol in hypertensive asthmatic patients. Pharmacodynamic effects on beta 2-adrenergic receptors.Hypertension. 1994 Sep;24(3):339-46. doi: 10.1161/01.hyp.24.3.339. Hypertension. 1994. PMID: 7916004 Clinical Trial.
-
Double-blind comparison of once-daily bopindolol and atenolol for mild-to-moderate hypertension.Int J Clin Pharmacol Ther Toxicol. 1987 Jun;25(6):347-52. Int J Clin Pharmacol Ther Toxicol. 1987. PMID: 2887520 Clinical Trial.
Cited by
-
Beta-blockers use in patients with chronic obstructive pulmonary disease and concomitant cardiovascular conditions.Int J Chron Obstruct Pulmon Dis. 2007;2(4):535-40. Int J Chron Obstruct Pulmon Dis. 2007. PMID: 18268926 Free PMC article. Review.
-
Cardioselective beta-blockers for chronic obstructive pulmonary disease.Cochrane Database Syst Rev. 2005 Oct 19;2005(4):CD003566. doi: 10.1002/14651858.CD003566.pub2. Cochrane Database Syst Rev. 2005. PMID: 16235327 Free PMC article.
-
Cardioselective beta-blocker use in patients with reversible airway disease.Cochrane Database Syst Rev. 2001;2002(2):CD002992. doi: 10.1002/14651858.CD002992. Cochrane Database Syst Rev. 2001. Update in: Cochrane Database Syst Rev. 2002;(1):CD002992. doi: 10.1002/14651858.CD002992. PMID: 11406056 Free PMC article. Updated.
-
Atenolol. A reappraisal of its pharmacological properties and therapeutic use in cardiovascular disorders.Drugs. 1991 Sep;42(3):468-510. doi: 10.2165/00003495-199142030-00007. Drugs. 1991. PMID: 1720383 Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
