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. 1984;312(5996):711-6.
doi: 10.1038/312711a0.

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

W Kruijer, J A Cooper, T Hunter, I M Verma

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

W Kruijer et al. Nature. 1984.

Abstract

Exposure of quiescent mouse fibroblasts to platelet-derived growth factor induces mRNA from the c-fos proto-oncogene within 10 min followed by synthesis of nuclear c-fos proteins. These are amongst the earliest described nuclear events that follow a mitogenic stimulus.

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