Augmentation of the in vitro activity of azlocillin against Bacteroides fragilis by clavulanic acid
- PMID: 6517552
- PMCID: PMC179977
- DOI: 10.1128/AAC.26.4.606
Augmentation of the in vitro activity of azlocillin against Bacteroides fragilis by clavulanic acid
Abstract
Azlocillin was active against 90% of 154 strains of Bacteroides fragilis at a concentration of 64 micrograms/ml. Twenty-eight strains of B. fragilis with an azlocillin MIC of greater than or equal to 8 micrograms/ml were retested with a combination of azlocillin plus clavulanic acid. Of these strains, 71% showed a 4- to 32-fold decrease in the MIC of azlocillin plus clavulanic acid.
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