[Relations between parasitism of the rat by Strongyloides ratti, female sex hormones and blood corticosterone]

Abstract

Situated under strict conditions in order to try to limit experimental aggravation and to respect the accomplishment of an endocrine balance, the experiments carried out study the influence on parasitism by Strongyloides ratti of ovariectomie and the treatments, of female rats castrated or not, by oestradiol, hexoestrol, diethylstilboestrol, progesterone, mestranol, chlormadinone association. Similarly, adrenal cortex reactions (corticosterone) to the treatment and parasitism are recorded. The analysis of the results lead to the thought that the glucocorticosteroid function of adrenal cortex could be one of the relays between gonades and the development of parasitism (intensity, removal of parasites).