Hydrogen bonding interactions of polyamines with the 2' OH of RNA
- PMID: 652523
- PMCID: PMC342079
- DOI: 10.1093/nar/5.4.1315
Hydrogen bonding interactions of polyamines with the 2' OH of RNA
Abstract
Polyamines and other charged amines bind to RNA by hydrogen bonding to the 3' phosphate and to the 2' OH. This mode of binding suggests a mechanism by which DNA and RNA might be distinguished by enzymes.
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