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Case Reports
. 1984 Dec;19(7):320-5.

Malignant transformation of an optic nerve melanocytoma

D J Apple, J M Craythorn, J J Reidy, R L Steinmetz, S E Brady, W A Bohart
  • PMID: 6525581
Case Reports

Malignant transformation of an optic nerve melanocytoma

D J Apple et al. Can J Ophthalmol. 1984 Dec.

Abstract

A 47-year-old woman who had had a flat, hyperpigmented lesion of the optic disc and juxtapapillary choroid for at least 17 years experienced acute visual loss. This was caused by rapid growth of a pigmented tumour emanating from the original lesion. Histopathological examination of the enucleated globe revealed a large malignant melanoma originating from a melanocytoma (magnocellular nevus) within the optic nerve and peripapillary choroid. This case represents a very rare instance of malignant transformation of a normally benign tumour.

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